Nashville Fertility

Recurrent Pregnancy Loss

Recurrent Pregnancy Loss is Defined as 2 or More Miscarriages Before 20 Weeks Gestation.

There are many potential reasons this happens, or it may happen and a cause is never found. Testing to find a cause may involve some or all of the tests below, depending on your situation and the information known about your losses.

Recurrent Pregnancy Loss Testing May Include:

Anatomic

  • Saline Infusion Sonogram (SIS)
  • Hysterosalpingogram

Endocrine

  • Thyroid Testing (TSH)
  • Serum progesterone or endometrial biopsy

Immunologic Testing

  • Lupus Anticoagulant (LAC)
  • Anticardiolipin Antibodies (ACA)
  • Antiphospholipid Antibody Panel (APA)

Chromosomal

  • Blood test on both partners for karyotype

Infection

  • Empiric treatment with antibiotics for possible persistent infection
  • Chlamydia/GC/Mycoplasma/Ureaplasma cultures

Thrombophilia Testing

  • Protein C
  • Protein S
  • Antithrombin III
  • Factor V Leiden mutation
  • Prothrombin (Factor II) mutation
  • PAI -1 Gene Mutation
  • MTHFR

 

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