Nashville Fertility

Saline Infusion Sonogram (SIS)

Saline Infusion Sonogram

A saline-infusion sonogram (SIS) may also be called a Hydrosonogram or Saline infusion sonohysterography (SHG). This test is an ultrasound study of the uterus and uterine cavity. This test does not evaluate the fallopian tubes. Abnormalities such as fibroids, uterine polyps and scarring can be detected with this test. All of these abnormalities are things that could interfere with embryo implantation and fertility.

Scheduling a SIS

The SIS is scheduled between cycle days 5-11 of your menstrual cycle. Please call the main number at NFC at the onset of your menses to schedule this appointment.


A small catheter is placed in the cervix, and sterile saline is infused into the uterus at the same time an ultrasound is being performed. The saline allows for distension and visualization of the uterine cavity.


The doctor or nurse practitioner performing the exam will review the results with you immediately. If an abnormality is discovered, you may need a follow up appointment to discuss the implications.

Side Effects

Mild cramping is the most commonly reported side effect, but most of our patients do not have any problems during or after this exam. You may take a cramp medication of your choice 30 minutes to an hour before your appointment. You should not need a driver and you can expect to continue normal activities afterwards.

ASRM Patient Fact Sheet – SIS

(615) 321-4740